For research use only.

Applications: WB, IHC  

Species Cross-Reactivity: H,M,R    

Molecular Weight: ~42KD     

Isotype: IgG1

Storage Buffer & Condition: PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.

Store : -20°C. Do not aliquot the antibody.

Recommended dilutions: WB: 1:1000  IHC: 1:200

Optimal dilutions should be determined by the end user.

Specificity: The CDX2 Mouse Monoclonal antibody detects endogenous CDX2 proteins. 

Background: CDX2 is a caudal type homeobox gene that encodes an intestine-specific transcription factor

that is expressed early in intestinal development and may be involved in the regulation of proliferation and

differentiation of intestinal epithelial cells. It is expressed in the nuclei of epithelial cells throughout the intestine,

from duodenum to rectum. The CDX2 protein is expressed in primary and metastatic colorectal carcinomas and

has also been demonstrated in the intestinal metaplasia of the stomach and intestinal-type gastric cancer,

while it is not expressed in the normal gastric mucosa. Studies have shown that CDX2 is superior

marker compared to CK20.

Applications:WB-Western blot   IHC-Immunochemistry   IF-Immunofluorescence   IP-Immunoprecipitation

                           ChIP-Chormatin Immunoprecipitation

Reactivity:   H-Human R-Rat M-Mouse Mk-Monkey Dg-Dog Ch-Chicken Hm-Hamster Rb-Rabbit Sh-Sheep