For research use only.

Application: IHC  

Species Cross-Reactivity: H, R, M   

Molecular Weight: N/A         

Isotype: IgG1

Storage Buffer & Condition: PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.

Store : -20°C. Do not aliquot the antibody.

Recommended dilutions: IHC: 1:200

Optimal dilutions should be determined by the end user.

Specificity: CD5 Mouse Monoclonal Antibody detects endogenous CD5 proteins. 

Background: CD5 is a cluster of differentiation found on a subset of IgM-secreting B cells called B-1 cells,

and also on T cells. [1] B-1 cells have limited diversity of their B-cell receptor due to their lack of the enzyme

terminal deoxynucleotidyl transferase (TdT) and are potentially self-reactive. CD5 serves to mitigate activating

signals from the BCR so that the B-1 cells can only be activated by very strong stimuli (such as bacterial

proteins) and not by normal tissue proteins.

Applications:WB-Western blot   IHC-Immunochemistry   IF-Immunofluorescence   IP-Immunoprecipitation

                          ChIP-Chormatin Immunoprecipitation

Reactivity:   H-Human R-Rat M-Mouse Mk-Monkey Dg-Dog Ch-Chicken Hm-Hamster Rb-Rabbit Sh-Sheep