For research use only.

Applications: IHC  

Species Cross-Reactivity: H, M, R   

Molecular Weight: ~44KD     

Isotype: IgG1

Storage Buffer & Condition: PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.

Store : -20°C. Do not aliquot the antibody.

Recommended dilutions: IHC: 1:200

Optimal dilutions should be determined by the end user.

Specificity: The CK19 Mouse Monoclonal antibody detects endogenous CK19 proteins 

Background: This protein is a member of the keratin family. The type I cytokeratins consist of acidic proteins

which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest

known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed

in the periderm, the transiently superficial layer that envelopes the developing epidermis. Keratin 19 is not

expressed in hepatocytes, therefore, antibody to keratin 19 is useful in the identification of liver metastasis.

The degree of keratin 19 positivity in breast cancer distinguishes malignant from benign tumours. Keratin 19

is often co-expressed with keratin 7.

Applications:WB-Western blot   IHC-Immunochemistry   IF-Immunofluorescence   IP-Immunoprecipitation

                           ChIP-Chormatin Immunoprecipitation

Reactivity:   H-Human R-Rat M-Mouse Mk-Monkey Dg-Dog Ch-Chicken Hm-Hamster Rb-Rabbit Sh-Sheep