For research use only.

Applications: WB, IHC 

Species Cross-Reactivity: H, R, M    

Molecular Weight: 26KDa

Isotype: IgG1

Storage Buffer & Condition: PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.

Store : -20°C. Do not aliquot the antibody.

Recommended dilutions: WB: 1:1,000~2,000 IHC: 1:200

Optimal dilutions should be determined by the end user.

Specificity: Bcl-2 antibody detects endogenous Bcl-2 proteins 

Background: BCL2 is an integral outer mitochondrial membrane protein that blocks the apoptotic death of

some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2

to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. BCL2 suppresses apoptosis in

a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. It regulates cell

death by controlling the mitochondrial membrane permeability.

Applications:WB-Western blot   IHC-Immunochemistry   IF-Immunofluorescence   IP-Immunoprecipitation

                         ChIP-Chormatin Immunoprecipitation

Reactivity:   H-Human R-Rat M-Mouse Mk-Monkey Dg-Dog Ch-Chicken Hm-Hamster Rb-Rabbit Sh-Sheep