For research use only.

Applications: WB,IHC     

Species Cross-Reactivity: H,M,R   

Molecular Weight: ~92KD     

Isotype: IgG1

Storage Buffer & Condition: PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.

Store : -20°C. Do not aliquot the antibody.

Recommended dilutions: WB: 1:1,000 IHC: 1:200

Optimal dilutions should be determined by the end user.

Specificity: The β-Catenin Mouse Monoclonal antibody detects endogenous β-Catenin proteins. 

Background: The distinct peripheral cytosolic proteins, alpha, beta and gamma catenin (102, 94 and 86 kDa)

are found in many tissues and bind to the conserved cytoplasmic tail domain of the cell adhesion cadherins.

Catenins link E cadherin to other integral membrane or cytoplasmic proteins and are modulated by Wnt1

proto oncogene. The central core region of beta catenin is involved in mediation of cadherin catenin complex

interaction with EGFR. Beta-Catenin-mediated signalling is involved at several stages of vertebrate neural

development .

Applications:WB-Western blot   IHC-Immunochemistry   IF-Immunofluorescence   IP-Immunoprecipitation

                           ChIP-Chormatin Immunoprecipitation

Reactivity:   H-Human R-Rat M-Mouse Mk-Monkey Dg-Dog Ch-Chicken Hm-Hamster Rb-Rabbit Sh-Sheep