For research use only.

Applications: IHC  

Species Cross-Reactivity: H, M, R   

Molecular Weight: ~35-37KD 

Isotype: IgG1

Storage Buffer & Condition: PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.

Store : -20°C. Do not aliquot the antibody.

Recommended dilutions: IHC: 1:200

Optimal dilutions should be determined by the end user.

Specificity: The CD20 antibody detects endogenous CD20 proteins. 

Background: CD20 is a non glycosylated protein with a molecular weight of 35 or 37 kDa depending on the

degree of phosphorylation. Although not a member of the tetraspanin superfamily of cell surface receptors,

it crosses the cell membrane four times. The CD20 antigen is present on human pre B lymphocytes and on

B lymphocytes at all stages of maturation, except on plasma cells. Low level expression of the CD20 antigen

has been detected on normal T lymphocytes. The CD20 molecule is involved in regulation of B cell

differentiation, presumably via its reported function as a Ca 2+ channel subunit.

Applications:WB-Western blot   IHC-Immunochemistry   IF-Immunofluorescence   IP-Immunoprecipitation

                         ChIP-Chormatin Immunoprecipitation

Reactivity:   H-Human R-Rat M-Mouse Mk-Monkey Dg-Dog Ch-Chicken Hm-Hamster Rb-Rabbit Sh-Sheep