For research use only.

Applications: WB

Species Cross-Reactivity: H, R, M

Molecular Weight: 68KD

Isotype: IgG1

Storage Buffer & Condition: PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.

Store : -20°C. Do not aliquot the antibody.

Recommended dilutions: WB: 1: 2,000-5,000

Optimal dilutions should be determined by the end user.

Specificity: The Lamin B1 antibody can detects endogenous Lamin B1 protein. 

Background: The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner

 nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution.

During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated.

Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression.

Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins,B1.

Applications:WB-Western blot   IHC-Immunochemistry   IF-Immunofluorescence   IP-Immunoprecipitation   

                            ChIP-Chormatin Immunoprecipitation

Reactivity:   H-Human R-Rat M-Mouse Mk-Monkey Dg-Dog Ch-Chicken Hm-Hamster Rb-Rabbit Sh-Sheep